Top Definition
Verb. A side effect of extreme over indulgence in crystal meth or crack cocaine. Tweekers typically perform OCD-like activities centered around finding small quantities of drugs that were inadvertently "misplaced". Tweekers may be seen on all fours, searching in gutters, obsessively looking under various objects and so on. In certain circumstances, extreme tweeking resembles autism or catatonia.
Yo! Check out that tweeking crack ho!
po Slagathor Април 23, 2004
A character from the TV show "South Park". Tweek is the ADD kid, who is constantly twitching. He often rants and raves about things that only he sees, and is addicted to coffee. Tweek is in love with Craig, and they sex each other.
Wow. Tweek sure has sex with Craig a lot. It's hot.
po The Lord Of Spam Фабруар 16, 2006
losing oneself in a senseless task while under the influence of speed.
She would tweek all night cleaning the house and pulling apart electronic devices.
po chillcat Мај 29, 2003
the nervous ticks or twitching one experiances as they come down from a crystal methamphetamine binge.
pulling hairs out of their face; picking at their face; picking their nose...
po a former tweeker Новембар 28, 2003
Upper, crystal meth
can I have a bump of tweek?
po Cosmo Wash.DC Децембар 26, 2002
to adjust or fix
Let me just tweek your computer.
po Tracy Lukeman Октобар 20, 2003
When you can't twerk, so you have to push your buttcheeks up and down to make them look like they are bouncing.
Guy1: Is that girl twerking or what?
Guy2: Naw man she's tweeking...
po Uhhhhhh123 Фабруар 3, 2014

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