Top Definition
to give in to one's sexual urges in a quick manner; usually referring to females
dang i was with abby for 10 mintes when she was ready to give it up!
po the give it upper Март 2, 2004
7 more definitions
to cheer for someone, or what they bring to the game
Give it up to your dj on the 1-2s keepin it crunk for the party
po DJ Kayla Фабруар 29, 2004
A request for praise which can be issued either by the recieving party or a third party.
Give it up for my man DJ Mike!
po foxmajik Фабруар 28, 2004
Have sex
Man, she finally gave it up last night
po Lucky Charms Фабруар 29, 2004
To cease efforts now otherwise pointless
"Just give it up man, she's not interested in you."

"You'd better give it up, unless you're rollin' for a bitch-slap."
po Krispy Фабруар 29, 2004
give sex to
You're not getting your money till you give it up.
po Anonymous Јун 16, 2002
to give in to temptation
"Yo mane, that hizzo is expecting some chedda if she be givin it up
po MC Rizzle Март 3, 2004

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