Top Definition
Cooze is slang for wet horny pussy; vagina.

A cooze missile is a guy who is always getting laid. Pun of cruise missile. He's hung, his slick and he nails the cooze every time.
Barney: Have you met Tim? He's a total cooze missile.
Mark: Lucky bastard!
Sheila: do you have his digits?
po CrystalBlonde69 Април 29, 2012

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