Top Definition
E2
The colloquial name for Everything2, a community-based encyclopedia website at its peak between 1999 and 2001.
"E2" is generally how users on Everything2.com refer to the website.
po Saul Pieman Јун 13, 2007
1 more definition
E2
An E2 is when you have to take an emergency dump.
"I'll be right back, I got an E2 emergency!"
po redneckpunk Новембар 9, 2006

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